By A. Gullo
Developing sectors within the in depth care box - and in serious care medication commonly - require particular degrees of competence having a similar universal denominator: an in-depth wisdom of human pathophysiology. even though this quantity provides lots of themes in consistent evolution, as witnessed by way of the gathering of chapters compiled via a number of researchers, this version contains, specifically, fields within which selection making on the patient’s bedside prevails over theoretical argumentation. In different phrases, the 1st and ultimate message this variation desires to offer is for the reader to concentration his/her realization on evidence-based medicine.
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Additional resources for Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: Proceedings of the 21st Postgraduate Course in Critical Medicine: Venice-Mestre, Italy - November 10-13, 2006
Over the last few decades, it has been shown that respiratory mechanics can be easily measured in intubated, mechanically ventilated patients with simple and widely available equipment [3–5]. The most popular method of measuring respiratory mechanics in relaxed, mechanically ventilated patients is rapid airway occlusion during constant flow inflation . e. the elastance of the respiratory system . Similarly, airway resistance can be measured with the rapid airway occlusion technique during constant flow inflation [6, 7].
The benefits of the use of PEEP come in part from the resulting increase in FRC. The shape of the P–V curve and the value of LIP may vary according to the end-expiratory lung volume that marks the beginning of inspiration . Increasing PEEP values can eliminate the LIP and decrease the compliance at the linear portion of the curve. These phenomena may theoretically reflect recruitment of some parts of the lung and distension or overdistension of other regions. The effect of PEEP on LIP may indicate good lung recruitment [14, 31, 32].
However, the mode and settings of a ventilator can significantly influence the course of a disease and the ultimate clinical outcome and may cause severe, life-threatening complications. Monitoring and comprehending respiratory mechanics during artificial ventilation may give some guidance to understanding of the patient’s pathophysiology or may promote techniques that counter the deterioration in gas exchange, but it can also help in minimising ventilator-induced complications. Over the last few decades, it has been shown that respiratory mechanics can be easily measured in intubated, mechanically ventilated patients with simple and widely available equipment [3–5].